From the category archives:

Breast Cancer Vaccine


A new vaccine against breast cancer has shown promising results during trials, according to the Karolinska Institute in Stockholm, Sweden. The results of the study was published in the journal Oncogene in May.

For breast cancer cells to proliferate they need to stimulate blood flow by forming of new veins to carry that blood.  But if you block the protein Delta-like ligand 4 (DLL4) you can create new – but useless – veins.  This slows down the tumor’s growth and may prevent breast cancer recurrence following surgery, according to Dr. Kristian Pietras who lead the study, since the tumor, despite new veins, does not receive the nourishment from an increased blood supply.

The animal experiments also showed that the vaccine had no serious side effects and that wounds still healed well.

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